Spatial complexity and control of a bacterial cell cycle

被引：43

作者：

Collier, Justine ^{[1
]}

Shapiro, Lucy ^{[1
]}

机构：

[1] Stanford Univ, Dept Dev Biol, Sch Med, Beckman Ctr, Stanford, CA 94305 USA

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2007年 / 18卷 / 04期

关键词：

D O I：

10.1016/j.copbio.2007.07.007

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A major breakthrough in understanding the bacterial cell cycle is the discovery that bacteria exhibit a high degree of intracellular organization. Chromosomal loci and many protein complexes are positioned at particular subcellular sites. In this review, we examine recently discovered control mechanisms that make use of dynamically localized protein complexes to orchestrate the Caulobacter crescentus cell cycle. Protein localization, notably of signal transduction proteins, chromosome partition proteins, and proteases, serves to coordinate cell division with chromosome replication and cell differentiation. The developmental fate of daughter cells is decided before completion of cytokinesis, via the early establishment of cell polarity by the distribution of activated signaling proteins, bacterial cytoskeleton, and landmark proteins.

引用

页码：333 / 340

页数：8

共 42 条

[11] Regulated degradation of chromosome replication proteins DnaA and CtrA in Caulobacter crescentus [J].

Gorbatyuk, B ;

Marczynski, GT .

MOLECULAR MICROBIOLOGY, 2005, 55 (04) :1233-1245

[12] Physiological consequences of blocked Caulobacter crescentus dnaA expression, an essential DNA replication gene [J].

Gorbatyuk, B ;

Marczynski, GT .

MOLECULAR MICROBIOLOGY, 2001, 40 (02) :485-497

[13] The Caulobacter crescentus polar organelle development protein PodJ is differentially localized and is required for polar targeting of the PleC development regulator [J].

Hinz, AJ ;

Larson, DE ;

Smith, CS ;

Brun, YV .

MOLECULAR MICROBIOLOGY, 2003, 47 (04) :929-941

[14] Oscillating global regulators control the genetic circuit driving a bacterial cell cycle [J].

Holtzendorff, J ;

Hung, D ;

Brende, P ;

Reisenauer, A ;

Viollier, PH ;

McAdams, HH ;

Shapiro, L .

SCIENCE, 2004, 304 (5673) :983-987

[15] DnaA coordinates replication initiation and cell cycle transcription in Caulobacter crescentus [J].

Hottes, AK ;

Shapiro, L ;

McAdams, HH .

MOLECULAR MICROBIOLOGY, 2005, 58 (05) :1340-1353

[16] Bacterial birth scar proteins mark future flagellum assembly site [J].

Huitema, E ;

Pritchard, S ;

Matteson, D ;

Radhakrishnan, SK ;

Viollier, PH .

CELL, 2006, 124 (05) :1025-1037

[17] A signal transduction protein cues proteolytic events critical to Caulobacter cell cycle progression [J].

Hung, DY ;

Shapiro, L .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (20) :13160-13165

[18] A phospho-signaling pathway controls the localization and activity of a protease complex critical for bacterial cell cycle progression [J].

Iniesta, Antonio A. ;

McGrath, Patrick T. ;

Reisenauer, Ann ;

McAdams, Harley H. ;

Shapiro, Lucy .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (29) :10935-10940

[19] Functions of the CckA histidine kinase in Caulobacter cell cycle control [J].

Jacobs, C ;

Ausmees, N ;

Cordwell, SJ ;

Shapiro, L ;

Laub, MT .

MOLECULAR MICROBIOLOGY, 2003, 47 (05) :1279-1290

[20] An essential protease involved in bacterial cell-cycle control [J].

Jenal, U ;

Fuchs, T .

EMBO JOURNAL, 1998, 17 (19) :5658-5669

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