The reactions of semicarbazide and thiosemicarbazide with ferrocenyl-substituted α,β-enones

被引：25

作者：

Klimova, T ^{[1
]}

Klimova, EI

García, MM

Stivalet, JMM

Ramírez, LR

机构：

[1] Natl Autonomous Univ Mexico, Dept Chem, Mexico City 04510, DF, Mexico

[2] Natl Autonomous Univ Mexico, Inst Chem, Mexico City 04510, DF, Mexico

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2001年 / 633卷 / 1-2期

关键词：

ferrocene; semicarbazide; thiosemicarbazide; 1-carbamoyl-4,5-dihydropyrazole; 1-thiocarbamoyl-4,5-dihydropyrazole;

D O I：

10.1016/S0022-328X(01)01059-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Semicarbazide (hydrochloride) and thiosemicarbazide react with alpha,beta -unsaturated ketones of the ferrocene series in excess of ' BuOK to give 1-carbamoyl- and 1-thiocarbamoyl(ferrocenyl)-4,5-dihydropyrazoles. The condensation with thiosemicarbazide is accompanied by the fragmentation of the starting alpha,beta -enones resulting in ferrocenecarbaldehyde or acetylferrocene thiosemicarbazones. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：137 / 142

页数：6

共 14 条

[1] The structure of bicyclic ferrocenylmethylene substituted 2-pyrazolines and their reactions with azodicarboxylic acid N-phenylimide [J].

Klimova, EI ;

García, MM ;

Berestneva, TK ;

Toledano, CA ;

Toskano, RA ;

Ramírez, LR .

JOURNAL OF ORGANOMETALLIC CHEMISTRY, 1999, 585 (01) :106-114

[2] Asymmetrical induction in the synthesis of ferrocenyl-substituted bicyclic pyrazolines. E,Z-isomerization of the ferrocenylmethylidene fragment [J].

Klimova, EI ;

Garcia, MM ;

Klimova-Berestneva, T ;

Ramirez, LR ;

Toledano, SA ;

Toskano, RA .

RUSSIAN CHEMICAL BULLETIN, 1999, 48 (04) :761-766

[3]

KLIMOVA EI, 1996, RUSS CHEM B, V45, P2740

[4] BICYCLIC PYRAZOLINES, POTENTIAL CENTRAL NERVOUS-SYSTEM DEPRESSANTS AND ANTI-INFLAMMATORY AGENTS [J].

KRAPCHO, J ;

TURK, CF .

JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (02) :207-210

[5]

NESMEYANOV AN, 1978, DOKL AKAD NAUK SSSR+, V241, P1099

[6]

NESMEYANOV AN, 1981, B ACAD SCI USSR CH, V30, P215

[7]

NESMEYANOV AN, 1979, B ACAD SCI USSR CH, V28, P236

[8] COPPER (II) COMPLEX OF 1,1'-DIACETYLFERROCENE BIS (THIOSEMICARBAZONE) [J].

OMOTE, Y ;

KOBAYASH.R ;

SUGIYAMA, N .

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1973, 46 (09) :2896-2897

[9]

OSMAN AM, 1976, INDIAN J CHEM B, V14, P282

[10]

OSZBACH G, 1975, ACTA CHIM HUNG, V86, P449

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