A short and facile synthetic route to prenylated flavones.: Cyclodehydrogenation of prenylated 2′-hydroxychalcones by a hypervalent iodine reagent

被引：15

作者：

Gulácsi, K

Litkei, G

Antus, S

Gunda, TE

机构：

[1] Lajos Kossuth Univ, Dept Organ Chem, H-4010 Debrecen, Hungary

[2] Hungarian Acad Sci, Antibiot Res Grp, H-4010 Debrecen, Hungary

来源：

TETRAHEDRON | 1998年 / 54卷 / 45期

基金：

美国国家科学基金会;

关键词：

flavonoids; flavones; chalcones; hypervalent iodine;

D O I：

10.1016/S0040-4020(98)00853-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first synthesis of the prenylated flavones kanzonol-D (1), -E (3) and yinyanghuo-C (4) was accomplished by cyclodehydrogenation of the appropriately substituted 2'-hydroxychalcones 16, 14 and 11, respectively, in presence of phenyl-iodine(III) diacetate (PIDA) / potassium hydroxide in methanol. The synthesis of kanzonol-B (13) was also achieved from the 2'-hydroxychalcone 12. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：13867 / 13876

页数：10

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