Sulfur-containing compounds from Scorodocarpus borneensis and their antimicrobial activity

被引：14

作者：

Lim, H ^{[1
]}

Kubota, K

Kobayashi, A

Sugawara, F

机构：

[1] Ochanomizu Univ, Dept Nutr & Food Sci, Bunkyo Ku, Tokyo 112, Japan

[2] Sci Univ Tokyo, Dept Appl Biol Sci, Noda, Chiba 278, Japan

来源：

PHYTOCHEMISTRY | 1998年 / 48卷 / 05期

关键词：

Scorodocarpus borneensis; Olaceae; wood garlic; polysulfides; 2,4,5,7-tetrathiaoctane 4,4-dioxide; 5-thioxo-2,4,6-trithiaheptane 2,2-dioxide; antimicrobial activity;

D O I：

10.1016/S0031-9422(97)00961-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three novel sulfur-containing compounds were isolated from Scorodocarpus borneensis. Their chemical structures were determined to be 2,4,5,7-tetrathiaoctane 4,4-dioxide (CH3SCH2SO2SCH2SCH3, 1) and 5-thioxo-2,4,6-trithiaheptane 2,2-dioxide (CH3SO2CH2SCSSCH3, 2), while the other compound was assumed to be O-ethyl S-methylthiomethyl thiosulfite (CH3SCH2SS(O)OCH2CH3, 3) on the basis of spectroscopic data. This first isolation of compound 1 strongly suggests that S. borneensis possesses a polysulfide formation pathway similar to that of other Allium species. Compounds 1 and 2 exhibited antimicrobial activity against some bacteria and fungi. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：787 / 790

页数：4

共 10 条

[1] CHEMISTRY OF ALKYL THIOLSULFINATE ESTERS .6. PREPARATION AND SPECTRAL STUDIES [J].

BLOCK, E ;

OCONNOR, J .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1974, 96 (12) :3921-3929

[2] THE ORGANOSULFUR CHEMISTRY OF THE GENUS ALLIUM - IMPLICATIONS FOR THE ORGANIC-CHEMISTRY OF SULFUR [J].

BLOCK, E .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1992, 31 (09) :1135-1178

[3]

BURKILL IH, 1935, DICT EC PRODUCTS MAL, P1985

[4] INVESTIGATION OF HEAD-SPACE OF ROASTED MEAT .2. SYNTHESIS OF SUBSTITUTED 2,4,5-TRITHIA-HEXANES [J].

DUBS, P ;

STUSSI, R .

HELVETICA CHIMICA ACTA, 1978, 61 (07) :2351-2359

[5] DIPEPTIDE PRECURSOR OF GARLIC ODOR IN MARASMIUS SPECIES [J].

GMELIN, R ;

LUXA, HH ;

ROTH, K ;

HOFLE, G .

PHYTOCHEMISTRY, 1976, 15 (11) :1717-1721

[6] NEW ANTIMICROBIAL COMPOUND FROM SCORODOCARPUS-BORNEENSIS BECC [J].

KUBOTA, K ;

MATSUMOTO, M ;

UEDA, M ;

KOBAYASHI, A .

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1994, 58 (02) :430-431

[7] IDENTIFICATION AND ANTIMICROBIAL ACTIVITY OF THE VOLATILE FLAVOR CONSTITUENTS FROM SCORODOCARPUS-BORNEENSIS BECC [J].

KUBOTA, K ;

OHHIRA, S ;

KOBAYASHI, A .

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1994, 58 (04) :644-646

[8]

MIKOLAJCZYK M, 1974, SYNTHESIS-STUTTGART, P124

[9]

OAE S, 1972, TETRAHEDRON, V28, P3202

[10] AN ANTIFUNGAL COMPOUND FROM SHIITAKE (LENTINUS-EDODES) [J].

TAKAZAWA, H ;

TAJIMA, F ;

MIYASHITA, C .

YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 1982, 102 (05) :489-491

← 1 →