Biology and pathogenesis of chikungunya virus

被引：532

作者：

Schwartz, Olivier ^{[1
]}

Albert, Matthew L. ^{[1
]}

机构：

[1] Inst Pasteur, F-75724 Paris 15, France

来源：

NATURE REVIEWS MICROBIOLOGY | 2010年 / 8卷 / 07期

关键词：

SEMLIKI-FOREST-VIRUS; ROSS-RIVER-VIRUS; AEDES-ALBOPICTUS DIPTERA; REUNION-ISLAND OUTBREAK; TOLL-LIKE RECEPTOR-3; DENDRITIC CELLS; INDIAN-OCEAN; INTERFERON-PRODUCTION; FUSION PROTEIN; ALPHAVIRUS REPLICATION;

D O I：

10.1038/nrmicro2368

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Chikungunya virus (CHIKV) is a re-emerging mosquito-borne alphavirus responsible for a recent, unexpectedly severe epidemic in countries of the Indian Ocean region. Although many alphaviruses have been well studied, little was known about the biology and pathogenesis of CHIKV at the time of the 2005 outbreak. Over the past 5 years there has been a multidisciplinary effort aimed at deciphering the clinical, physiopathological, immunological and virological features of CHIKV infection. This Review highlights some of the most recent advances in our understanding of the biology of CHIKV and its interactions with the host.

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页码：491 / 500

页数：10

相关论文

共 138 条

[1] A virus-like particle vaccine for epidemic Chikungunya virus protects nonhuman primates against infection [J].

Akahata, Wataru ;

Yang, Zhi-Yong ;

Andersen, Hanne ;

Sun, Siyang ;

Holdaway, Heather A. ;

Kong, Wing-Pui ;

Lewis, Mark G. ;

Higgs, Stephen ;

Rossmann, Michael G. ;

Rao, Srinivas ;

Nabel, Gary J. .

NATURE MEDICINE, 2010, 16 (03) :334-U134

[2] Toll-like receptor signalling [J].

Akira, S ;

Takeda, K .

NATURE REVIEWS IMMUNOLOGY, 2004, 4 (07) :499-511

[3] Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3 [J].

Alexopoulou, L ;

Holt, AC ;

Medzhitov, R ;

Flavell, RA .

NATURE, 2001, 413 (6857) :732-738

[4] The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA [J].

Allen, Irving C. ;

Scull, Margaret A. ;

Moore, Chris B. ;

Holl, Eda K. ;

McElvania-TeKippe, Erin ;

Taxman, Debra J. ;

Guthrie, Elizabeth H. ;

Pickles, Raymond J. ;

Ting, Jenny P. -Y. .

IMMUNITY, 2009, 30 (04) :556-565

[5] Precipitation and temperature effects on populations of Aedes albopictus (Diptera: Culicidae):: Implications for range expansion [J].

Alto, BW ;

Juliano, SA .

JOURNAL OF MEDICAL ENTOMOLOGY, 2001, 38 (05) :646-656

[6] Temperature effects on the dynamics of Aedes albopictus (Diptera: Culicidae) populations in the laboratory [J].

Alto, BW ;

Juliano, SA .

JOURNAL OF MEDICAL ENTOMOLOGY, 2001, 38 (04) :548-556

[7]

Angelini P., 2008, Parassitologia (Rome), V50, P97

[8]

[Anonymous], 2006, Wkly Epidemiol Rec, V81, P409

[9] The serine proteinase inhibitor (Serpin) plasminogen activation inhibitor type 2 protects against viral cytopathic effects by constitutive interferon α/β priming [J].

Antalis, TM ;

La Linn, M ;

Donnan, K ;

Mateo, L ;

Gardner, J ;

Dickinson, JL ;

Buttigieg, K ;

Suhrbier, A .

JOURNAL OF EXPERIMENTAL MEDICINE, 1998, 187 (11) :1799-1811

[10] Expression of the zinc-finger antiviral protein inhibits alphavirus replication [J].

Bick, MJ ;

Carroll, JWN ;

Gao, GX ;

Goff, SP ;

Rice, CM ;

MacDonald, MR .

JOURNAL OF VIROLOGY, 2003, 77 (21) :11555-11562

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