Current Place of Beta-Blockers in the Treatment of Hypertension

被引:24
作者
Bielecka-Dabrowa, Agata [1 ]
Aronow, Wilbert S. [2 ]
Rysz, Jacek [3 ]
Banach, Maciej [1 ]
机构
[1] Med Univ Lodz, Dept Hypertens, PL-90549 Lodz, Poland
[2] New York Med Coll, Div Cardiol, Valhalla, NY 10595 USA
[3] Med Univ Lodz, Dept Nephrol Hypertens & Family Med, PL-90549 Lodz, Poland
关键词
Hypertension; antihypertensive treatment; beta-blocker; cardiovascular risk; AMBULATORY BLOOD-PRESSURE; IMPAIRED FASTING GLUCOSE; NITRIC-OXIDE RELEASE; END-POINT REDUCTION; MYOCARDIAL-INFARCTION; HEART-FAILURE; CARDIOVASCULAR EVENTS; PRIMARY PREVENTION; LOSARTAN INTERVENTION; ANTIHYPERTENSIVE DRUG;
D O I
10.2174/157016110793563861
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Hypertension represents the most common cardiovascular risk factor, affecting more than 25% of the adult population in developed societies. Although beta-blockers have been previously shown to effectively reduce blood pressure and have been used for hypertension treatment for over 40 years, their effect on cardiovascular morbidity and mortality in hypertensive patients remains controversial and their use in uncomplicated hypertension is currently still under debate. According to the previous recommendations beta-blockers should not be preferred as first-line therapy in hypertension patients. This review summarizes the current knowledge on application of beta-blockers in patients with hypertension and discusses the most recent guidelines of the European Society of Hypertension (2009) on beta-blockers applications.
引用
收藏
页码:733 / 741
页数:9
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