Substituted 1-allyl-2-allenylbenzenes via palladium-catalyzed allylallenylation of benzyne derivatives

被引：26

作者：

Jeganmohan, M ^{[1
]}

Cheng, CH ^{[1
]}

机构：

[1] Natl Tsing Hua Univ, Dept Chem, Hsinchu 30013, Taiwan

来源：

SYNTHESIS-STUTTGART | 2005年 / 10期

关键词：

1,6-enynes; allylalkylation; palladium; benzyne; allylic chlorides; alkynylstannanes;

D O I：

10.1055/s-2005-869966

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient method for the synthesis of 1-allyl-2-allenyl benzenes via palladium-catalyzed three-component assembly of benzynes, allyl chlorides, and allenylstannanes is described. Substituted benzyne precursors 1a-e undergo three-component assembly with various allylic chlorides 2a-e and allenylstannanes in the presence of Pd(dba)(2)/dppe (5 mol%), and cesium fluoride in acetonitrile at ambient temperature affording 1-allyl-2-allenyl benzenes 4a-k in good to excellent yields. The possible mechanism for the present catalytic reaction is proposed.

引用

页码：1693 / 1697

页数：5

共 28 条

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