Sentinel lymph node mapping in gynecologic malignancies

被引:16
作者
Loar, P. V. [1 ]
Reynolds, R. K., III [1 ]
机构
[1] Univ Michigan, Dept Obstet & Gynecol, Div Gynecol Oncol, Ann Arbor, MI 48109 USA
关键词
sentinel node; Gynecologic oncology; vulvar carcinoma; cervical carcinoma; endometrial carcinoma;
D O I
10.1016/j.ijgo.2007.06.001
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Lymph node status is the most important prognostic factor for women with vulvar, cervical and endometrial carcinoma and complete lymph node dissection has historically been an integral part of the surgical treatment of these diseases. Lymphadenectomy can be morbid for patients, who may experience wound breakdown, lymphocyst formation or chronic lymphedema, among other problems. Sentinel lymph node mapping is a newer technology that allows selective removal of the first node draining a tumor thereby allowing a potentially less aggressive procedure to be performed. Sentinel node mapping is well accepted for the management of breast carcinoma and cutaneous melanoma, and has resulted in reduced morbidity without adversely affecting survival. Sentinel node mapping is currently being investigated for treatment of gynecologic cancers. Recent studies show promise for incorporating the sentinel node mapping technique for treatment of several gynecologic malignancies. (C) 2007 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:69 / 74
页数:6
相关论文
共 40 条
[11]   Sentinel lymph node procedure is highly accurate in squamous cell carcinoma of the vulva [J].
de Hullu, JA ;
Hollema, H ;
Piers, DA ;
Verheijen, RHM ;
van Diest, PJ ;
Mourits, MJE ;
Aalders, JG ;
van der Zee, AGJ .
JOURNAL OF CLINICAL ONCOLOGY, 2000, 18 (15) :2811-2816
[12]   Vulvar carcinoma - The price of less radical surgery [J].
de Hullu, JA ;
Hollema, H ;
Lolkema, S ;
Boezen, M ;
Boonstra, H ;
Burger, MPM ;
Aalders, JG ;
Mourits, MJE ;
van der Zee, AGJ .
CANCER, 2002, 95 (11) :2331-2338
[13]   A pilot study utilizing intraoperative lymphoscintigraphy for identification of the sentinel lymph nodes in vulvar cancer [J].
DeCesare, SL ;
Fiorica, JV ;
Roberts, WS ;
Reintgen, D ;
Arango, H ;
Hoffman, MS ;
Puleo, C ;
Cavanagh, D .
GYNECOLOGIC ONCOLOGY, 1997, 66 (03) :425-428
[14]   Lymph node mapping and sentinel node detection in patients with cervical carcinoma: A 2-year experience [J].
Di Stefano, AB ;
Acquaviva, G ;
Garozzo, G ;
Barbic, M ;
Cvjeticanin, B ;
Meglic, L ;
Kobal, B ;
Rakar, S .
GYNECOLOGIC ONCOLOGY, 2005, 99 (03) :671-679
[15]   ALTERNATE APPROACH TO EARLY CANCER OF THE VULVA [J].
DISAIA, PJ ;
CREASMAN, WT ;
RICH, WM .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1979, 133 (07) :825-832
[16]   Detection of sentinel lymph nodes with lymphazurin in cervical, uterine, and vulvar malignancies [J].
Echt, ML ;
Finan, MA ;
Hoffman, MS ;
Kline, RC ;
Roberts, WS ;
Fiorica, JV .
SOUTHERN MEDICAL JOURNAL, 1999, 92 (02) :204-208
[17]  
ESSLNER R, 2006, CLIN CANCER RES, V12, pS2320
[18]  
FIORICA J, 2001, OPER TECH GYNECOLOG, V6, P27
[19]   Lymphatic mapping and sentinel node biopsy in women with high-risk endometrial cancer [J].
Frumovitz, Michael ;
Bodurka, Diane C. ;
Broaddus, Russell R. ;
Coleman, Robert L. ;
Sood, Anil K. ;
Gershenson, David M. ;
Burke, Thomas W. ;
Levenback, Charles F. .
GYNECOLOGIC ONCOLOGY, 2007, 104 (01) :100-103
[20]   Groin recurrence in patients with vulvar cancer with negative nodes on superficial inguinal lymphadenectomy [J].
Gordinier, ME ;
Malpica, A ;
Burke, TW ;
Bodurka, DC ;
Wolf, JK ;
Jhingran, A ;
Ramirez, PT ;
Levenback, C .
GYNECOLOGIC ONCOLOGY, 2003, 90 (03) :625-628