Stent Thrombosis

被引：332

作者：

Holmes, David R., Jr. ^{[1
]}

Kereiakes, Dean J. ^{[2
]}

Garg, Scot ^{[4
]}

Serruys, Patrick W. ^{[4
]}

Dehmer, Gregory J. ^{[5
]}

Ellis, Stephen G. ^{[3
]}

Williams, David O. ^{[6
]}

Kimura, Takeshi ^{[7
]}

Moliterno, David J. ^{[8
]}

机构：

[1] Mayo Clin, Div Cardiovasc Dis Internal Med, Rochester, MN 55905 USA

[2] Christ Hosp, Heart & Vasc Ctr, Cincinnati, OH 45219 USA

[3] Cleveland Clin, Dept Cardiovasc Med, Cleveland, OH 44106 USA

[4] Erasmus MC, Thoraxctr, Dept Intervent Cardiol, Rotterdam, Netherlands

[5] Scott & White Mem Hosp & Clin, Div Cardiol, Temple, TX USA

[6] Brigham & Womens Hosp, Div Cardiovasc, Boston, MA 02115 USA

[7] Kyoto Univ Hosp, Dept Cardiovasc Med, Kyoto 606, Japan

[8] Univ Kentucky, Dept Med, Div Cardiol, Lexington, KY 40506 USA

来源：

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | 2010年 / 56卷 / 17期

关键词：

acute myocardial infarction; bare-metal stent; drugeluting stent; dual antiplatelet therapy; percutaneous coronary intervention; stent thrombosis; DRUG-ELUTING STENT; ELEVATION MYOCARDIAL-INFARCTION; DUAL ANTIPLATELET THERAPY; BARE-METAL STENTS; PERCUTANEOUS CORONARY INTERVENTION; ROUTINE CLINICAL-PRACTICE; LONG-TERM OUTCOMES; POOLED ANALYSIS; RESPONSE VARIABILITY; CLOPIDOGREL THERAPY;

D O I：

10.1016/j.jacc.2010.07.016

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Intense investigation continues on the pathobiology of stent thrombosis (ST) because of its morbidity and mortality. Because little advance has been made in outcomes following ST, ongoing research is focused on further understanding predictive factors as well as ST frequency and timing in various patient subsets, depending upon whether a drug-eluting stent or bare-metal stent has been implanted. Although the preventive role of antiplatelet therapies remains unchallenged, new data on genomics and variability in response to antiplatelet therapy, as well as the effects of novel therapeutic agents and duration of therapy, have become available. The goal remains identification of patients at particularly increased risk of ST so that optimal prevention strategies can be developed and employed. © 2010 American College of Cardiology Foundation.

引用

页码：1357 / 1365

页数：9

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