Effects of allylic and homoallylic substituents on the ring closing metathesis reaction used to synthesise simplified eleuthesides

被引：45

作者：

Caggiano, L ^{[1
]}

Castoldi, D ^{[1
]}

Beumer, R ^{[1
]}

Bayón, P ^{[1
]}

Tesler, J ^{[1
]}

Gennari, C ^{[1
]}

机构：

[1] Univ Milan, Ctr Eccellenza CISI, Ist CNR Sci & Tecnol Mol, Dipartimento Chim Organ & Ind, I-20133 Milan, Italy

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 43期

关键词：

ring closing metathesis; protective groups; p-methoxyphenyl (PMP); antitumour compounds;

D O I：

10.1016/j.tetlet.2003.09.010

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

During the course of our synthetic studies towards simplified eleuthesides, we have found that p-methoxyphenyl (PMP) protected allylic alcohols are compatible with the RCM reaction and can give better yields than the corresponding free allylic alcohols. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：7913 / 7919

页数：7

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