Tautomers of one-electron-oxidized guanosine

被引：53

作者：

Chatgilialoglu, C ^{[1
]}

Caminal, C ^{[1
]}

Guerra, M ^{[1
]}

Mulazzani, QG ^{[1
]}

机构：

[1] CNR, ISOQ, I-40129 Bologna, Italy

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 37期

关键词：

density functional calculations; kinetics; nucleosides; pulse radiolysis; tautomerism;

D O I：

10.1002/anie.200501087

中图分类号：

O6 [化学];

学科分类号：

0703 [化学];

摘要：

(Chemical Equation Presented) Aminic or iminic: Two tautomeric forms of oxidized guanosine have been produced by chemical radiation methods - by direct oxidation of guanosine or from the protonation of the 8-bromoguanosine electron adduct - and identified. The tautomerization from the iminic to the aminic arrangement has an activation energy of 23.0 kJ mol-1 and occurs through a complex transition state (see scheme). © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

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页码：6030 / 6032

页数：3

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