Metabolic pathways: does the actual Gibbs free-energy change affect the flux rate?

被引:8
作者
Aledo, JC [1 ]
机构
[1] Univ Malaga, Fac Ciencias, Dept Bioquim & Biol Mol, E-29071 Malaga, Spain
关键词
energy dissipation; irreversible thermodynamics; control flux;
D O I
10.1111/j.1539-3429.2001.tb00100.x
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Energy dissipation fulfils an important function in metabolism driving the flux of matter through metabolic pathways. The flux rate is a multivariable function. One of such variables affecting the flux is the actual free energy change. A particular case of metabolic pathway is analysed to illustrate this fact, using only general enzymic and thermodynamic concepts. (C) 2001 IUBMB. Published by Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:142 / 143
页数:2
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