Tandem multi-step synthesis of C-carboxyazlactones promoted by N-heterocyclic carbenes

被引：40

作者：

Campbell, Craig D. ^{[1
]}

Duguet, Nicolas ^{[1
]}

Gallagher, Katherine A. ^{[1
]}

Thomson, Jennifer E. ^{[1
]}

Lindsay, Anita G. ^{[2
]}

O'Donoghue, AnnMarie C. ^{[2
]}

Smith, Andrew D. ^{[1
]}

机构：

[1] Univ St Andrews, EaStCHEM, Sch Chem, St Andrews KY16 9ST, Fife, Scotland

[2] Univ Durham, Dept Chem, Univ Sci Labs, Durham DH1 3LE, England

来源：

CHEMICAL COMMUNICATIONS | 2008年 / 30期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1039/b806816j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Cascade reaction sequences incorporating N-heterocyclic carbene-based organocatalysis have been developed that allow the direct preparation of a range of (+/-)-4-phenoxycarbonylazlactones in good isolated yields (66-84%) from the corresponding N-p-anisoyl amino acids.

引用

页码：3528 / 3530

页数：3

共 43 条

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