One-pot three-component synthesis of 3-Amino-5,8-dioxo-5,8-dihydro-1H-pyrazolo[1,2-a]pyridazines

被引：21

作者：

Adib, Mehdi

Koloogani, Somayeh Aali

Abbasi, Alireza

Bijanzadeh, Hamid Reza

机构：

[1] Univ Tehran, Univ Tehran Coll Sci, Sch Chem, Tehran, Iran

[2] Tarbiat Modares Univ, Dept Chem, Tehran, Iran

来源：

SYNTHESIS-STUTTGART | 2007年 / 19期

关键词：

multicomponent reactions; pyrazolo[1,2-alpyridazines; isocyanides; cyclizations; heterocycles;

D O I：

10.1055/s-2007-990775

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reactive 1: 1 zwitterionic intermediate formed by the addition of isocyanides to dialkyl acetylenedicarboxylates was trapped by 3,6-dihydroxypyridazine to produce 3-amino-5,8-dioxo-5,8-dihydro- 1 H-pyrazolo[ 1,2-alpha]pyridazines in good yields.

引用

页码：3056 / 3060

页数：5

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