Anc1 interacts with the catalytic subunits of the general transcription factors TFIID and TFIIF, the chromatin remodeling complexes RSC and INO80, and the histone acetyltransferase complex NuA3

被引：40

作者：

Kabani, M ^{[1
]}

Michot, K ^{[1
]}

Boschiero, C ^{[1
]}

Werner, M ^{[1
]}

机构：

[1] CEA Saclay, Lab Physiogenom, Serv Biochim & Genet Mol, Dept Biol Joliot Curie, F-91191 Gif Sur Yvette, France

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 2005年 / 332卷 / 02期

关键词：

general transcription factors; RNA polyrnerase II; Saccharomyces cerevisiae; chromatin remodeling; histone acetyltransferase; Ancl;

D O I：

10.1016/j.bbrc.2005.04.158

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Ancl protein co-purifies with general transcription factors, chromatin remodeling complexes, and historic modification enzymes and is required for efficient transcription in yeast. We show here that Ancl interacts with Tsm1, Tfg1, Sth1, Inc,80, and Sas3 that are, respectively, the catalytic subunits of the general transcription factors TFIID and TFII F, of the chromatin remodeling complexes RSC and INO80, and of the historic H3-acetyltransferase complex NuA3. We show that Ancl is required for growth oil galactose as the sole carbon source, and that it is recruited to the UAS of the GAL1 gene after induction. (C) 2005 Elsevier Inc. All rights reserved.

引用

页码：398 / 403

页数：6

共 26 条

[21] Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner [J].