NeuroAid (MLC601) versus piracetam in the recovery of post-infarct homonymous hemianopsia

被引:18
作者
Ghandehari, Kavian [1 ]
Mood, Zahra Izadi [2 ]
Ebrahimzadeh, Saeed [3 ]
Picard, David [4 ,5 ]
Zhang, Yue [4 ,5 ]
机构
[1] Mashhad Univ Med Sci, Neurosci Res Ctr, Mashhad, Iran
[2] Mashhad Univ Med Sci, Dept Tradit Med, Mashhad, Iran
[3] Mashhad Univ Med Sci, Dept Biostat, Mashhad, Iran
[4] Natl Neurosci Inst, Singapore, Singapore
[5] Moleac Ltd, Singapore 138667, Singapore
关键词
MLC601; piracetam; post-infarct recovery; stroke; DOUBLE-BLIND; STROKE; INVESTIGATE; EFFICACY;
D O I
10.3969/j.issn.1673-5374.2011.06.003
中图分类号
Q2 [细胞生物学];
学科分类号
071013 [干细胞生物学];
摘要
In the clinic, the natural recovery rate of homonymous hemianopsia caused by occipital lobe infarction is low. At present, ideal therapeutic effects of piracetam for improving visual field defects following homonymous hemianopsia do not exist. The present randomized, controlled study compared the effects of NeuroAid (MLC601) versus piracetam for improving visual field defects in post-infarct homonymous hemianopsia patients matched for age and sex. After 3 months of treatment with NeuroAid (MLC601) or piracetam, visual field defects were significantly improved, compared with prior to treatment (P < 0.001). After treatment with MLC601, relative reduction of right and left visual field defects was 45% and 45.7%, respectively, while relative reduction after treatment with piracetam was 32.7% and 30.3%, respectively. These findings suggested that MLC601 was superior to piracetam for reducing visual field defects in homonymous hemianopsia patients.
引用
收藏
页码:418 / 422
页数:5
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