In the clinic, the natural recovery rate of homonymous hemianopsia caused by occipital lobe infarction is low. At present, ideal therapeutic effects of piracetam for improving visual field defects following homonymous hemianopsia do not exist. The present randomized, controlled study compared the effects of NeuroAid (MLC601) versus piracetam for improving visual field defects in post-infarct homonymous hemianopsia patients matched for age and sex. After 3 months of treatment with NeuroAid (MLC601) or piracetam, visual field defects were significantly improved, compared with prior to treatment (P < 0.001). After treatment with MLC601, relative reduction of right and left visual field defects was 45% and 45.7%, respectively, while relative reduction after treatment with piracetam was 32.7% and 30.3%, respectively. These findings suggested that MLC601 was superior to piracetam for reducing visual field defects in homonymous hemianopsia patients.
机构:
Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Clin Res Ctr, Singapore 117597, SingaporeNatl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Clin Res Ctr, Singapore 117597, Singapore
Chen, Christopher
;
Venketasubramanian, N.
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机构:
Natl Inst Neurosci, Dept Neurol, Singapore, SingaporeNatl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Clin Res Ctr, Singapore 117597, Singapore
Venketasubramanian, N.
;
Gan, Robert N.
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机构:
Natl Inst Neurosci, Dept Neurol, Singapore, SingaporeNatl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Clin Res Ctr, Singapore 117597, Singapore
Gan, Robert N.
;
Lambert, Caroline
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机构:
Moleac, Singapore, SingaporeNatl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Clin Res Ctr, Singapore 117597, Singapore
Lambert, Caroline
;
Picard, David
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h-index: 0
机构:
Moleac, Singapore, SingaporeNatl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Clin Res Ctr, Singapore 117597, Singapore
Picard, David
;
Chan, Bernard P. L.
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h-index: 0
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Natl Univ Singapore Hosp, Div Neurol, Singapore, SingaporeNatl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Clin Res Ctr, Singapore 117597, Singapore
Chan, Bernard P. L.
;
Chan, Edwin
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机构:
Evidence Based Med, Clin Trials & Epidemiol Res Unit, Singapore, SingaporeNatl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Clin Res Ctr, Singapore 117597, Singapore
Chan, Edwin
;
Bousser, Marie G.
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h-index: 0
机构:
Hop Lariboisiere, F-75475 Paris, FranceNatl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Clin Res Ctr, Singapore 117597, Singapore
Bousser, Marie G.
;
Shi Xuemin
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机构:
Univ Tradit Chinese Med, Tianjin, Peoples R ChinaNatl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Clin Res Ctr, Singapore 117597, Singapore
机构:
Ang Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, SingaporeAng Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, Singapore
Kong, Keng He
;
Wee, Seng Kwee
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Ang Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, SingaporeAng Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, Singapore
Wee, Seng Kwee
;
Ng, Chwee Yin
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Ang Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, SingaporeAng Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, Singapore
Ng, Chwee Yin
;
Chua, Karen
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Ang Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, SingaporeAng Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, Singapore
Chua, Karen
;
Chan, Kay Fei
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Ang Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, SingaporeAng Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, Singapore
Chan, Kay Fei
;
Venketasubramanian, N.
论文数: 0引用数: 0
h-index: 0
机构:
Natl Univ Singapore Hosp, Div Neurol, Singapore 117548, SingaporeAng Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, Singapore
Venketasubramanian, N.
;
Chen, Christopher
论文数: 0引用数: 0
h-index: 0
机构:
Natl Univ Singapore Hosp, Dept Pharmacol, Singapore 117548, SingaporeAng Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, Singapore
机构:
Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Clin Res Ctr, Singapore 117597, SingaporeNatl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Clin Res Ctr, Singapore 117597, Singapore
Chen, Christopher
;
Venketasubramanian, N.
论文数: 0引用数: 0
h-index: 0
机构:
Natl Inst Neurosci, Dept Neurol, Singapore, SingaporeNatl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Clin Res Ctr, Singapore 117597, Singapore
Venketasubramanian, N.
;
Gan, Robert N.
论文数: 0引用数: 0
h-index: 0
机构:
Natl Inst Neurosci, Dept Neurol, Singapore, SingaporeNatl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Clin Res Ctr, Singapore 117597, Singapore
Gan, Robert N.
;
Lambert, Caroline
论文数: 0引用数: 0
h-index: 0
机构:
Moleac, Singapore, SingaporeNatl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Clin Res Ctr, Singapore 117597, Singapore
Lambert, Caroline
;
Picard, David
论文数: 0引用数: 0
h-index: 0
机构:
Moleac, Singapore, SingaporeNatl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Clin Res Ctr, Singapore 117597, Singapore
Picard, David
;
Chan, Bernard P. L.
论文数: 0引用数: 0
h-index: 0
机构:
Natl Univ Singapore Hosp, Div Neurol, Singapore, SingaporeNatl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Clin Res Ctr, Singapore 117597, Singapore
Chan, Bernard P. L.
;
Chan, Edwin
论文数: 0引用数: 0
h-index: 0
机构:
Evidence Based Med, Clin Trials & Epidemiol Res Unit, Singapore, SingaporeNatl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Clin Res Ctr, Singapore 117597, Singapore
Chan, Edwin
;
Bousser, Marie G.
论文数: 0引用数: 0
h-index: 0
机构:
Hop Lariboisiere, F-75475 Paris, FranceNatl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Clin Res Ctr, Singapore 117597, Singapore
Bousser, Marie G.
;
Shi Xuemin
论文数: 0引用数: 0
h-index: 0
机构:
Univ Tradit Chinese Med, Tianjin, Peoples R ChinaNatl Univ Singapore, Yong Loo Lin Sch Med, Dept Pharmacol, Clin Res Ctr, Singapore 117597, Singapore
机构:
Ang Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, SingaporeAng Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, Singapore
Kong, Keng He
;
Wee, Seng Kwee
论文数: 0引用数: 0
h-index: 0
机构:
Ang Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, SingaporeAng Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, Singapore
Wee, Seng Kwee
;
Ng, Chwee Yin
论文数: 0引用数: 0
h-index: 0
机构:
Ang Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, SingaporeAng Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, Singapore
Ng, Chwee Yin
;
Chua, Karen
论文数: 0引用数: 0
h-index: 0
机构:
Ang Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, SingaporeAng Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, Singapore
Chua, Karen
;
Chan, Kay Fei
论文数: 0引用数: 0
h-index: 0
机构:
Ang Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, SingaporeAng Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, Singapore
Chan, Kay Fei
;
Venketasubramanian, N.
论文数: 0引用数: 0
h-index: 0
机构:
Natl Univ Singapore Hosp, Div Neurol, Singapore 117548, SingaporeAng Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, Singapore
Venketasubramanian, N.
;
Chen, Christopher
论文数: 0引用数: 0
h-index: 0
机构:
Natl Univ Singapore Hosp, Dept Pharmacol, Singapore 117548, SingaporeAng Mo Kio Hosp, Rehabil Ctr, Tan Tock Seng Hosp, Singapore 569766, Singapore