Sparse evidence of MERS-CoV infection among animal workers living in Southern Saudi Arabia during 2012

被引：28

作者：

Memish, Ziad A. ^{[1
,2
]}

Alsahly, Ahmad ^{[3
]}

al Masri, Malak ^{[1
]}

Heil, Gary L. ^{[4
]}

Anderson, Benjamin D. ^{[4
]}

Peiris, Malik ^{[5
,6
]}

Khan, Salah Uddin ^{[4
,7
]}

Gray, Gregory C. ^{[4
]}

机构：

[1] Minist Hlth, Riyadh, Saudi Arabia

[2] Alfaisal Univ, Coll Med, Riyadh, Saudi Arabia

[3] Reg Hlth Directorate, Jazan, Saudi Arabia

[4] Univ Florida, Emerging Pathogens Inst, Coll Publ Hlth & Hlth Profess, Gainesville, FL USA

[5] Univ Hong Kong, Sch Publ Hlth, Hong Kong, Hong Kong, Peoples R China

[6] Univ Hong Kong, HKU Pasteur Res Pole, Hong Kong, Hong Kong, Peoples R China

[7] ICDDR B, Ctr Communicable Dis, Dhaka, Bangladesh

来源：

INFLUENZA AND OTHER RESPIRATORY VIRUSES | 2015年 / 9卷 / 02期

关键词：

antibody; Kingdom of Saudi Arabia; MERS-CoV; pseudoparticle virus neutralization assays; DROMEDARY CAMELS; CORONAVIRUS; ANTIBODIES;

D O I：

10.1111/irv.12287

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging viral pathogen that primarily causes respiratory illness. We conducted a seroprevalence study of banked human serum samples collected in 2012 from Southern Saudi Arabia. Sera from 300 animal workers (17% with daily camel exposure) and 50 non-animal-exposed controls were examined for serological evidence of MERS-CoV infection by a pseudoparticle MERS-CoV spike protein neutralization assay.None of the sera reproducibly neutralized the MERS-CoV-pseudotyped lentiviral vector. These data suggest that serological evidence of zoonotic transmission of MERS-CoV was not common among animal workers in Southern Saudi Arabia during July 2012.

引用

页码：64 / 67

页数：4

共 12 条

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