Protein fate in neurodegenerative proteinopathies: Polyglutamine diseases join the (mis)fold

被引：164

作者：

Paulson, HL ^{[1
]}

机构：

[1] Univ Iowa, Coll Med, Dept Neurol, Iowa City, IA 52242 USA

来源：

AMERICAN JOURNAL OF HUMAN GENETICS | 1999年 / 64卷 / 02期

关键词：

D O I：

10.1086/302269

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

[No abstract available]

引用

页码：339 / 345

页数：7

共 38 条

[31] Genetic neurodegenerative diseases: The human illness and transgenic models [J].

Price, DL ;

Sisodia, SS ;

Borchelt, DR .

SCIENCE, 1998, 282 (5391) :1079-1083

[32] Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA [J].

Reddy, PH ;

Williams, M ;

Charles, V ;

Garrett, L ;

Pike-Buchanan, L ;

Whetsell, WO ;

Miller, G ;

Tagle, DA .

NATURE GENETICS, 1998, 20 (02) :198-202

[33] Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions [J].

Saudou, F ;

Finkbeiner, S ;

Devys, D ;

Greenberg, ME .

CELL, 1998, 95 (01) :55-66

[34] Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo [J].

Scherzinger, E ;

Lurz, R ;

Turmaine, M ;

Mangiarini, L ;

Hollenbach, B ;

Hasenbank, R ;

Bates, GP ;

Davies, SW ;

Lehrach, H ;

Wanker, EE .

CELL, 1997, 90 (03) :549-558

[35] SH3GL3 associates with the huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates [J].

Sittler, A ;

Walter, S ;

Wedemeyer, N ;

Hasenbank, R ;

Scherzinger, E ;

Eickhoff, H ;

Bates, GP ;

Lehrach, H ;

Wanker, EE .

MOLECULAR CELL, 1998, 2 (04) :427-436

[36] POLYGLUTAMINE EXPANSION AS A PATHOLOGICAL EPITOPE IN HUNTINGTONS-DISEASE AND 4 DOMINANT CEREBELLAR ATAXIAS [J].

TROTTIER, Y ;

LUTZ, Y ;

STEVANIN, G ;

IMBERT, G ;

DEVYS, D ;

CANCEL, G ;

SAUDOU, F ;

WEBER, C ;

DAVID, G ;

TORA, L ;

AGID, Y ;

BRICE, A ;

MANDEL, JL .

NATURE, 1995, 378 (6555) :403-406

[37] Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila [J].

Warrick, JM ;

Paulson, HL ;

Gray-Board, GL ;

Bui, QT ;

Fischbeck, KH ;

Pittman, RN ;

Bonini, NM .

CELL, 1998, 93 (06) :939-949

[38] Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract [J].

Wellington, CL ;

Ellerby, LM ;

Hackam, AS ;

Margolis, RL ;

Trifiro, MA ;

Singaraja, R ;

McCutcheon, K ;

Salvesen, GS ;

Propp, SS ;

Bromm, M ;

Rowland, KJ ;

Zhang, TQ ;

Rasper, D ;

Roy, S ;

Thornberry, N ;

Pinsky, L ;

Kakizuka, A ;

Ross, CA ;

Nicholson, DW ;

Bredesen, DE ;

Hayden, MR .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (15) :9158-9167

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