Oxidative coupling of arylboronic acids with arenes via Rh-catalyzed direct C-H arylation

被引：150

作者：

Vogler, Thomas ^{[1
]}

Studer, Armido ^{[1
]}

机构：

[1] Univ Munster, Inst Organ Chem, Fachbereich Chem, D-48149 Munster, Germany

来源：

ORGANIC LETTERS | 2008年 / 10卷 / 01期

关键词：

D O I：

10.1021/ol702659a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Oxidative coupling of three different arenes and a thiophene derivative with various arylboronic acids was achieved with a [RhCl(C2H4)(2)](2)/ P[p-(CF3)C6H4](3) catalyst system. Commercially available 2,2,6,6-tetramethylpiperidine-N-oxyl radical (TEMPO) was used as a stoichiometric oxidant. A 2-pyridyl group and an imine functional group served as ortho-directing groups to mediate the direct C-H arylation by a Rh complex. Moderate to excellent yields were obtained for the coupling reactions.

引用

页码：129 / 131

页数：3

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