Bioinformatics - A user's perspective

被引:16
作者
Kaminski, N [1 ]
机构
[1] Chaim Sheba Med Ctr, Inst Resp Med, Funct Genom Unit, IL-52621 Tel Hashomer, Israel
[2] Univ Calif San Francisco, Lung Biol Ctr, San Francisco, CA 94143 USA
关键词
D O I
10.1165/ajrcmb.23.6.4291
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This review provides an overview of bioinformatics from the user's point of view. Bioinformatics, defined as the application of computers, databases, and computational methods to the management of biologic information, is essential for almost every aspect of data management in modern biology. The rapid accumulation of genomic sequence information together with the wide availability of new technologies that analyze global gene expression patterns have created an information overload. Molecular biology labs are increasingly dependent on computers, large-capacity databases, search and analysis tools, and high-quality Internet connections. Currently available bioinformatics tools are discussed and a general approach is outlined. Using the resources and approaches in this review, readers should be able to form their own view of bioinformatics and tailor the solutions to the information overload according to their needs.
引用
收藏
页码:705 / 711
页数:7
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