Molecular epidemiology of Haemophilus influenzae type b isolated from children with clinical cases of conjugate vaccine failures

被引：8

作者：

Campos, J ^{[1
]}

Aracil, B ^{[1
]}

Román, F ^{[1
]}

Pérez-Vázquez, M ^{[1
]}

机构：

[1] Ctr Nac Microbiol, Inst Salud Carlos 3, Ctr Nacl Microbiol, Madrid, Spain

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2003年 / 41卷 / 08期

关键词：

D O I：

10.1128/JCM.41.8.3915-3918.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We analyzed eight invasive Haemophilus influenzae strains isolated from individual children vaccinated appropriately for their ages. Five of the strains were type b and three were nontypeable strains. Children infected with nontypeable strains had a protective level of anti-H. influenzae type b antibodies, while only one of the children whose cases represented true vaccine failure did.

引用

页码：3915 / 3918

页数：4

共 21 条

[11] Clinical and immunological risk factors associated with Haemophilus influenzae type b conjugate vaccine failure in childhood [J].

Heath, PT ;

Booy, R ;

Griffiths, H ;

Clutterbuck, E ;

Azzopardi, HJ ;

Slack, MPE ;

Fogarty, J ;

Moloney, AC ;

Moxon, ER .

CLINICAL INFECTIOUS DISEASES, 2000, 31 (04) :973-980

[12] The UK Hib vaccine experience [J].

Heath, PT ;

McVernon, J .

ARCHIVES OF DISEASE IN CHILDHOOD, 2002, 86 (06) :396-399

[13]

KAYHTY H, 1983, J INFECT DIS, V147, P1100

[14] CAPSULAR TYPING OF HAEMOPHILUS-INFLUENZAE WITH A DNA PROBE [J].

KROLL, JS ;

ELY, S ;

MOXON, ER .

MOLECULAR AND CELLULAR PROBES, 1991, 5 (05) :375-379

[15] Identification of Haemophilus influenzae serotypes by standard slide agglutination serotyping and PCR-based capsule typing [J].

LaClaire, LL ;

Tondella, MLC ;

Beall, DS ;

Noble, CA ;

Raghunathan, PL ;

Rosenstein, NE ;

Popovic, T .

JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (01) :393-396

[16] SIMPLE METHOD FOR CONSTRUCTING PHYLOGENETIC TREES FROM DISTANCE MATRICES [J].

LI, WH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (02) :1085-1089

[17] Reduced effectiveness of Haemophilus influenzae type b conjugate vaccine in children with a high prevalence of human immunodeficiency virus type 1 infection [J].

Madhi, SA ;

Petersen, K ;

Khoosal, M ;

Huebner, RE ;

Mbelle, N ;

Mothupi, R ;

Saloojee, H ;

Crewe-Brown, H ;

Klugman, KP .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2002, 21 (04) :315-321

[18] Adaptation of Bordetella pertussis to vaccination:: A cause for its reemergence? [J].

Mooi, FR ;

van Loo, IHM ;

King, AJ .

EMERGING INFECTIOUS DISEASES, 2001, 7 (03) :526-528

[19]

MUSSER JM, 1990, REV INFECT DIS, V12, P75

[20] Worldwide Haemophilus influenzae type b disease at the beginning of the 21st century:: Global analysis of the disease burden 25 years after the use of the polysaccharide vaccine and a decade after the advent of conjugates [J].

Peltola, H .

CLINICAL MICROBIOLOGY REVIEWS, 2000, 13 (02) :302-+

← 1 2 3 →