Touch and go: tying TonB to transport

被引:244
作者
Postle, K
Kadner, RJ
机构
[1] Univ Virginia, Dept Microbiol, Charlottesville, VA 22908 USA
[2] Washington State Univ, Sch Mol Biosci, Pullman, WA 99164 USA
关键词
D O I
10.1046/j.1365-2958.2003.03629.x
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The TonB system of Gram-negative bacteria appears to exist for the purpose of transducing the protonmotive force energy from the cytoplasmic membrane, where it is generated, to the outer membrane, where it is needed for active transport of iron siderophores, vitamin B12 and, in pathogens, iron from host-binding proteins. In this review, we bring the reader up to date on the developments in the field since the authors each wrote reviews in this journal in 1990.
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页码:869 / 882
页数:14
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