A protein farnesyl transferase involved in abscisic acid signal transduction in Arabidopsis

被引：320

作者：

Cutler, S ^{[1
]}

Ghassemian, M ^{[1
]}

Bonetta, D ^{[1
]}

Cooney, S ^{[1
]}

McCourt, P ^{[1
]}

机构：

[1] UNIV TORONTO, DEPT BOT, TORONTO, ON M5S 3B2, CANADA

来源：

SCIENCE | 1996年 / 273卷 / 5279期

关键词：

D O I：

10.1126/science.273.5279.1239

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The hormone abscisic acid (ABA) modulates a variety of developmental processes and responses to environmental stress in higher plants. A collection of mutations, designated era, in Arabidopsis thaliana that confer an enhanced response to exogenous ABA includes mutations in the Era1 gene, which encodes the beta subunit of a protein farnesyl transferase. In yeast and mammalian systems, farnesyl transferases modify several signal transduction proteins for membrane localization. The era1 mutants suggest that a negative regulator of ABA sensitivity must be acted on by a farnesyl transferase to function.

引用

页码：1239 / 1241

页数：3

共 27 条

[11] RAM2, AN ESSENTIAL GENE OF YEAST, AND RAM1 ENCODE THE 2 POLYPEPTIDE COMPONENTS OF THE FARNESYLTRANSFERASE THAT PRENYLATES A-FACTOR AND RAS PROTEINS
HE, B
CHEN, P
CHEN, SY
VANCURA, KL
MICHAELIS, S
POWERS, S
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (24) : 11373 - 11377
[12] ISOPRENYLATION IN REGULATION OF SIGNAL TRANSDUCTION BY G-PROTEIN-COUPLED RECEPTOR KINASES
INGLESE, J
KOCH, WJ
CARON, MG
LEFKOWITZ, RJ
[J]. NATURE, 1992, 359 (6391) : 147 - 150
[13] CHANGES IN CYTOSOLIC PH AND CALCIUM OF GUARD-CELLS PRECEDE STOMATAL MOVEMENTS
IRVING, HR
GEHRING, CA
PARISH, RW
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (05) : 1790 - 1794
[14] Koornneef M., 1994, ARABIDOPSIS, P313
[15] REQUIREMENT FOR RAS IN RAF ACTIVATION IS OVERCOME BY TARGETING RAF TO THE PLASMA-MEMBRANE
LEEVERS, SJ
PATERSON, HF
MARSHALL, CJ
[J]. NATURE, 1994, 369 (6479) : 411 - 414
[16] ARABIDOPSIS ABA RESPONSE GENE ABI1 - FEATURES OF A CALCIUM-MODULATED PROTEIN PHOSPHATASE
LEUNG, J
BOUVIERDURAND, M
MORRIS, PC
GUERRIER, D
CHEFDOR, F
GIRAUDAT, J
[J]. SCIENCE, 1994, 264 (5164) : 1448 - 1452
[17] A PROTEIN PHOSPHATASE 2C INVOLVED IN ABA SIGNAL-TRANSDUCTION IN ARABIDOPSIS-THALIANA
MEYER, K
LEUBE, MP
GRILL, E
[J]. SCIENCE, 1994, 264 (5164) : 1452 - 1455
[18] REGULATION OF GENE-EXPRESSION PROGRAMS DURING ARABIDOPSIS SEED DEVELOPMENT - ROLES OF THE ABI3 LOCUS AND OF ENDOGENOUS ABSCISIC-ACID
PARCY, F
VALON, C
RAYNAL, M
GAUBIERCOMELLA, P
DELSENY, M
GIRAUDAT, J
[J]. PLANT CELL, 1994, 6 (11) : 1567 - 1582
[19] RANDALL SK, 1993, PLANT CELL, V5, P433, DOI 10.1105/tpc.5.4.433
[20] PROTEIN PRENYLATION - GENES, ENZYMES, TARGETS, AND FUNCTIONS
SCHAFER, WR
RINE, J
[J]. ANNUAL REVIEW OF GENETICS, 1992, 26 : 209 - 237

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