PDZBase: a protein-protein interaction database for PDZ-domains

被引:157
作者
Beuming, T
Skrabanek, L
Niv, MY
Mukherjee, P
Weinstein, H
机构
[1] Cornell Univ, Weill Med Coll, Dept Physiol & Biophys, New York, NY 10021 USA
[2] Cornell Univ, Weill Med Coll, Inst Computat Biomed, New York, NY 10021 USA
关键词
D O I
10.1093/bioinformatics/bti098
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
PDZBase is a database that aims to contain all known PDZ-domain-mediated protein-protein interactions. Currently, PDZBase contains approximately 300 such interactions, which have been manually extracted from > 200 articles. The database can be queried through both sequence motif and keyword-based searches, and the sequences of interacting proteins can be visually inspected through alignments (for the comparison of several interactions), or as residue-based diagrams including schematic secondary structure information (for individual complexes).
引用
收藏
页码:827 / 828
页数:2
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