Detection and sequence analysis of hepatitis B virus integration in peripheral blood mononuclear cells

被引：35

作者：

Laskus, T

Radkowski, M

Wang, LF

Nowicki, M

Rakela, J

机构：

[1] Univ Pittsburgh, Med Ctr, Div Gastroenterol & Hepatol, Pittsburgh, PA 15213 USA

[2] Inst Infect Dis, Warsaw, Poland

[3] Univ So Calif, Maternal Child Virol Res Lab, Los Angeles, CA 90033 USA

来源：

JOURNAL OF VIROLOGY | 1999年 / 73卷 / 02期

关键词：

D O I：

10.1128/JVI.73.2.1235-1238.1999

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A PCR-based technique was used to detect hepatitis B virus (HBV) integration in peripheral blood mononuclear cells from patients with chronic hepatitis B. Integrated HBV DNA sequences, with virus-cell junctions located in the cohesive region between direct repeat 1 (DR1) and DR2, were found in 2 of 10 studied patients.

引用

收藏

页码：1235 / 1238

页数：4

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