Neuroscience - A painful factor

被引:8
作者
Torsney, C [1 ]
MacDermott, AB [1 ]
机构
[1] Columbia Univ, Ctr Neurobiol & Behav, Dept Physiol & Cellular Biophys, New York, NY 10032 USA
关键词
D O I
10.1038/438923a
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Neurology
引用
收藏
页码:923 / 925
页数:3
相关论文
共 8 条
[1]   BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain [J].
Coull, JAM ;
Beggs, S ;
Boudreau, D ;
Boivin, D ;
Tsuda, M ;
Inoue, K ;
Gravel, C ;
Salter, MW ;
De Koninck, Y .
NATURE, 2005, 438 (7070) :1017-1021
[2]   Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain [J].
Coull, JAM ;
Boudreau, D ;
Bachand, K ;
Prescott, SA ;
Nault, F ;
Sik, A ;
De Koninck, P ;
De Koninck, Y .
NATURE, 2003, 424 (6951) :938-942
[3]   Setting the tone: superficial dorsal horn projection neurons regulate pain sensitivity [J].
Mantyh, PW ;
Hunt, SP .
TRENDS IN NEUROSCIENCES, 2004, 27 (10) :582-584
[4]   Ceramide activates microglia to enhance the production/secretion of brain-derived neurotrophic factor (BDNF) without induction of deleterious factors in vitro [J].
Nakajima, K ;
Tohyama, Y ;
Kohsaka, S ;
Kurihara, T .
JOURNAL OF NEUROCHEMISTRY, 2002, 80 (04) :697-705
[5]   BDNF-induced TrkB activation down-regulates the K+-Cl- cotransporter KCC2 and impairs neuronal Cl- extrusion [J].
Rivera, C ;
Li, H ;
Thomas-Crusells, J ;
Lahtinen, H ;
Viitanen, T ;
Nanobashvili, A ;
Kokaia, Z ;
Airaksinen, MS ;
Voipio, J ;
Kaila, K ;
Saarma, M .
JOURNAL OF CELL BIOLOGY, 2002, 159 (05) :747-752
[6]   Can we conquer pain? [J].
Scholz, J ;
Woolf, CJ .
NATURE NEUROSCIENCE, 2002, 5 (Suppl 11) :1062-1067
[7]   Brain-derived neurotrophic factor is an endogenous modulator of nociceptive responses in the spinal cord [J].
Thompson, SWN ;
Bennett, DLH ;
Kerr, BJ ;
Bradbury, EJ ;
McMahon, SB .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (14) :7714-7718
[8]   P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury [J].
Tsuda, M ;
Shigemoto-Mogami, Y ;
Koizumi, S ;
Mizokoshi, A ;
Kohsaka, S ;
Salter, MW ;
Inoue, K .
NATURE, 2003, 424 (6950) :778-783