Nutrient-Sensing Mechanisms across Evolution

被引：296

作者：

Chantranupong, Lynne ^{[1
,2
,3
,4
]}

Wolfson, Rachel L. ^{[1
,2
,3
,4
]}

Sabatini, David M. ^{[1
,2
,3
,4
]}

机构：

[1] Whitehead Inst Biomed Res, Cambridge, MA 02142 USA

[2] MIT, Cambridge Ctr 9, Dept Biol, Cambridge, MA 02142 USA

[3] MIT, Dept Biol, Howard Hughes Med Inst, Cambridge, MA 02139 USA

[4] Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA

来源：

CELL | 2015年 / 161卷 / 01期

关键词：

ACTIVATED PROTEIN-KINASE; GLUTAMINE-SYNTHETASE ADENYLYLATION; SIGNAL-TRANSDUCTION PROTEINS; ADENYLATE ENERGY-CHARGE; AMINO-ACID DEPRIVATION; GTP-BINDING PROTEINS; P70; S6; KINASE; SACCHAROMYCES-CEREVISIAE; ESCHERICHIA-COLI; FISSION YEAST;

D O I：

10.1016/j.cell.2015.02.041

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

For organisms to coordinate their growth and development with nutrient availability, they must be able to sense nutrient levels in their environment. Here, we review select nutrient-sensing mechanisms in a few diverse organisms. We discuss how these mechanisms reflect the nutrient requirements of specific species and how they have adapted to the emergence of multicellularity in eukaryotes.

引用

页码：67 / 83

页数：17

共 247 条

[1]

SUPPRESSION OF RIBOSOMAL REINITIATION AT UPSTREAM OPEN READING FRAMES IN AMINO ACID-STARVED CELLS FORMS THE BASIS FOR GCN4 TRANSLATIONAL CONTROL [J].

ABASTADO, JP ;

MILLER, PF ;

JACKSON, BM ;

HINNEBUSCH, AG .

MOLECULAR AND CELLULAR BIOLOGY, 1991, 11 (01) :486-496

[2]

Amino acid signaling in yeast:: Casein kinase I and the Ssy5 endoprotease are key determinants of endoproteolytic activation of the membrane-bound Stp1 transcription factor [J].

Abdel-Sater, F ;

Bakkoury, ME ;

Urrestarazu, A ;

Vissers, S ;

André, B .

MOLECULAR AND CELLULAR BIOLOGY, 2004, 24 (22) :9771-9785

[3]

Amino Acid Signaling in Yeast: Activation of Ssy5 Protease Is Associated with Its Phosphorylation-induced Ubiquitylation [J].

Abdel-Sater, Fadi ;

Jean, Cathy ;

Merhi, Ahmad ;

Vissers, Stephan ;

Andre, Bruno .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (14) :12006-12015

[4]

ADLER SP, 1975, J BIOL CHEM, V250, P6264

[5]

Kinetic basis for the stimulatory effect of phosphorylation on the methylesterase activity of CheB [J].

Anand, GS ;

Stock, AM .

BIOCHEMISTRY, 2002, 41 (21) :6752-6760

[6]

AMP-activated protein kinase plays a role in the control of food intake [J].

Andersson, U ;

Filipsson, K ;

Abbott, CR ;

Woods, A ;

Smith, K ;

Bloom, SR ;

Carling, D ;

Small, CJ .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (13) :12005-12008

[7]

Expression, purification and crystallization of the ammonium transporter Amt-1 from Archaeoglobus fulgidus [J].

Andrade, SLA ;

Dickmanns, A ;

Ficner, R ;

Einsle, O .

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 2005, 61 :861-863

[8]

Regulation of transcription factor latency by receptor-activated proteolysis [J].

Andreasson, Claes ;

Heessen, Stijn ;

Ljungdahl, Per O. .

GENES & DEVELOPMENT, 2006, 20 (12) :1563-1568

[9]

Preservation of liver protein synthesis during dietary leucine deprivation occurs at the expense of skeletal muscle mass in mice deleted for eIF2 kinase GCN2 [J].

Anthony, TG ;

McDaniel, BJ ;

Byerley, RL ;

McGrath, BC ;

Cavener, DDR ;

McNurlan, MA ;

Wek, RC .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (35) :36553-36561

[10]

A Tumor Suppressor Complex with GAP Activity for the Rag GTPases That Signal Amino Acid Sufficiency to mTORC1 [J].

Bar-Peled, Liron ;

Chantranupong, Lynne ;

Cherniack, Andrew D. ;

Chen, Walter W. ;

Ottina, Kathleen A. ;

Grabiner, Brian C. ;

Spear, Eric D. ;

Carter, Scott L. ;

Meyerson, Matthew ;

Sabatini, David M. .

SCIENCE, 2013, 340 (6136) :1100-1106

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