Gold nanoparticles induce oxidative damage in lung fibroblasts in vitro

被引：156

作者：

Li, Jasmine J. ^{[1
,3
]}

Zou, Li ^{[4
]}

Hartono, Deny ^{[2
]}

Ong, Choon-Nam ^{[4
]}

Bay, Boon-Huat ^{[3
]}

Yung, Lin-Yue Lanry ^{[1
,2
]}

机构：

[1] Natl Univ Singapore, Nanosci & Nanotechnol Initiat, Singapore 119260, Singapore

[2] Natl Univ Singapore, Dept Chem & Biomol Engn, Singapore 119260, Singapore

[3] Natl Univ Singapore, Dept Anat, Singapore 119260, Singapore

[4] Natl Univ Singapore, Dept Community Occupat & Family Med, Singapore 119260, Singapore

来源：

ADVANCED MATERIALS | 2008年 / 20卷 / 01期

关键词：

D O I：

10.1002/adma.200701853

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Evaluation of the health risks associated with the use of nanometer-sized particles constitutes an important research field. Here, the effect of gold nanoparticles (AuNPs) on human embryonic lung fibroblasts is investigated. The figure shows the uptake of AuNPs by lung fibroblasts. Most nanoparticles are endocytosed and found in vesicles (arrows) around the nucleus (N). However, some particles are found in cytosol (red circle).

引用

页码：138 / +

页数：6

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