Recent developments and applications of molecularly imprinted monolithic column for HPLC and CEC

被引：76

作者：

Zheng, Chao ^{[1
]}

Huang, Yan-Ping ^{[1
]}

Liu, Zhao-Sheng ^{[1
]}

机构：

[1] Tianjin Med Univ, Coll Pharm, Tianjin 300070, Peoples R China

来源：

JOURNAL OF SEPARATION SCIENCE | 2011年 / 34卷 / 16-17期

基金：

中国国家自然科学基金;

关键词：

CEC; Molecularly imprinted polymer; Monolithic column; Review; CAPILLARY ELECTROCHROMATOGRAPHIC SEPARATION; LIQUID-CHROMATOGRAPHIC SEPARATION; AMINO-ACID ENANTIOMERS; CHIRAL SEPARATION; RECOGNITION PROPERTIES; POLYMER MONOLITH; STATIONARY PHASES; SUSPENSION POLYMERIZATION; SELECTIVE RECOGNITION; PROTEIN RECOGNITION;

D O I：

10.1002/jssc.201100164

中图分类号：

O65 [分析化学];

学科分类号：

070302 [分析化学];

摘要：

As a new generation of stationary phases, monolithic supports have attracted significant interest in high-performance liquid chromatography (HPLC) and capillary electrochromatography (CEC) because of their ease of preparation, high reproducibility, versatile surface chemistry and rapid mass transport. Molecularly imprinted polymers (MIPs) are synthetic materials with high specific recognition ability to template molecule. The combination of monolithic column and MIPs integrates the high efficiency of modern chromatography and the high selectivity provided by MIPs. This review focuses on the recent developments and applications of all kinds of monolithic matrix, i.e. organic polymer-based and silica-based MIP monolith in HPLC and CEC mode.

引用

页码：1988 / 2002

页数：15

共 149 条

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Molecularly imprinted polymers by suspension polymerisation in perfluorocarbon liquids, with emphasis on the influence of the porogenic solvent [J].