Microwave-assisted Michael reactions of 3-(2′-nitrovinyl)indole with indoles on TLC-grade silica gel.: A new, facile synthesis of 2,2-bis(3′-indolyl)nitroethanes

被引：65

作者：

Chakrabarty, M ^{[1
]}

Basak, R ^{[1
]}

Ghosh, N ^{[1
]}

机构：

[1] Bose Inst, Dept Chem, Kolkata 700009, W Bengal, India

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 23期

关键词：

nitrovinylindole; microwave; solid surface; Michael reaction; bisindolynitroethanes;

D O I：

10.1016/S0040-4039(01)00581-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3-(2 ' -Nitrovinyl)indole reacted with indole and 1- and 2-alkylindoles on TLC-grade silica gel under microwave irradiation to furnish in 7-10 min bis(indolyl)nitroethanes in high yields (70 86%). The same products were also obtained in 69-84% yields without microwave irradiation, but the reactions required 8-14 h for completion. Skatole was inert under both sets of conditions. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：3913 / 3915

页数：3

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