Droplet-based nano/picoliter mixer using hydrophobic microcapillary vent

被引:35
作者
Hosokawa, K [1 ]
Fujii, T [1 ]
Endo, I [1 ]
机构
[1] RIKEN, Inst Phys & Chem Res, Biochem Syst Lab, Wako, Saitama 3510198, Japan
来源
MEMS '99: TWELFTH IEEE INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS, TECHNICAL DIGEST | 1999年
关键词
D O I
10.1109/MEMSYS.1999.746860
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
A mixing device for liquid droplets with pL-nL volume was developed for the first time. Two droplets with volume of 5 nL were pneumatically manipulated and joined together in a microchannel. For drawing off the air between two droplets, Hydrophobic Microcapillary Vent (HMCV)-a vent valve driven by the negative capillary action-was utilized. The mixer can be used as a diffusion-based optical chemical detector, or as a basic component in integrated multistep Micro Total Analysis Systems (mu TAS). Since the mixer has planar structure without moving parts, it can be fabricated by molding technique at low cost.
引用
收藏
页码:388 / 393
页数:6
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