Optical manipulation and fusion of liposomes as microreactors

被引：77

作者：

Kulin, S ^{[1
]}

Kishore, R

Helmerson, K

Locascio, L

机构：

[1] NIST, Phys Lab, Gaithersburg, MD 20899 USA

[2] NIST, Chem Sci & Technol Lab, Gaithersburg, MD 20899 USA

来源：

LANGMUIR | 2003年 / 19卷 / 20期

关键词：

D O I：

10.1021/la0344433

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We present an all-optical method to manipulate and fuse giant liposomes, typically 10 mum in diameter. Optical tweezers are used to trap two individual liposomes, which are then brought into contact. A single pulse of ultraviolet laser light focused on the adjoining membranes induces the fusion between the liposomes. As a consequence, the chemical reagents encapsulated in the two liposomes mix and a chemical reaction takes place.

引用

收藏

页码：8206 / 8210

页数：5

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