Perfusion CT and acute stroke imaging: Foundations, applications, and literature review

被引：104

作者：

Donahue, Joseph ^{[1
]}

Wintermark, Max ^{[1
,2
]}

机构：

[1] Univ Virginia, Div Neuroradiol, Charlottesville, VA 22908 USA

[2] Stanford Univ, Div Neuroradiol, Dept Radiol, Stanford, CA 94305 USA

来源：

JOURNAL OF NEURORADIOLOGY | 2015年 / 42卷 / 01期

关键词：

Perfusion imaging; Cerebrovascular accident; Cerebrovascular circulation; Acute ischemic stroke imaging; ACUTE ISCHEMIC-STROKE; ARTERIAL INPUT FUNCTION; ACUTE CEREBRAL-ISCHEMIA; TISSUE-PLASMINOGEN ACTIVATOR; COMPUTED-TOMOGRAPHY SCORE; INTRAVENOUS THROMBOLYSIS; HEMORRHAGIC TRANSFORMATION; ENDOVASCULAR TREATMENT; INFARCT CORE; INTERVENTIONAL MANAGEMENT;

D O I：

10.1016/j.neurad.2014.11.003

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

100204 [神经病学];

摘要：

Multimodal CT features prominently in the rapidly evolving field of acute stroke triage, with perfusion CT applications at the forefront of many clinical research efforts. Perfusion CT offers a time sensitive and widely practicable assessment of cerebral hemodynamics and parenchymal viability that is key in acute stroke management. The following article reviews perfusion CT foundations and technical considerations while highlighting recent modality advances and frontline clinical applications. Ischemic penumbra and other prognostic imaging biomarkers are discussed in the context of results of recent clinical trials (MR-RESCUE, IMS III, Tenecteplase, etc.), with an emphasis on evidence based image guided stroke triage. (C) 2015 Elsevier Masson SAS. All rights reserved.

引用

页码：21 / 29

页数：9

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