Oxidative C-H activation/C-C bond forming reactions: Synthetic scope and mechanistic insights

被引：727

作者：

Kalyani, D ^{[1
]}

Deprez, NR ^{[1
]}

Desai, LV ^{[1
]}

Sanford, MS ^{[1
]}

机构：

[1] Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 127卷 / 20期

关键词：

D O I：

10.1021/ja051402f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This paper describes a new palladium-catalyzed method for C-H activation/carbon-carbon bond formation with hypervalent iodine arylating agents. This transformation has been applied to a variety of arene and benzylic substrates containing different directing groups (pyridines, quinolines, oxazolidinones, and amides) and proceeds with high levels of regiocontrol. Mechanistic experiments provide preliminary evidence in support of an unusual mechanism for this transformation involving a Pd(II)/Pd(IV) catalytic cycle. Copyright © 2005 American Chemical Society.

引用

页码：7330 / 7331

页数：2

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