Specific and sensitive diagnosis of schistosome infection: can it be done with antibodies?

被引：228

作者：

Doenhoff, MJ ^{[1
]}

Chiodini, PL

Hamilton, JV

机构：

[1] Univ Wales, Sch Biol Sci, Bangor LL57 2UW, Gwynedd, Wales

[2] Hosp Trop Dis, London WC1E 6UA, England

[3] Univ London London Sch Hyg & Trop Med, London WC1E 7HT, England

[4] Univ Wales, Inst Biol Sci, Aberystwyth SY23 3DA, Ceredigion, Wales

来源：

TRENDS IN PARASITOLOGY | 2004年 / 20卷 / 01期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/j.pt.2003.10.019

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

A simple, cheap, sensitive and specific assay for routine diagnosis of schistosome infection is not yet available. This review considers some of the advantages and disadvantages of parasitological microscopy, circulating-antigen detection and antibody-detection methods. Immunoassays for the detection of antibodies reactive against schistosome egg antigens have the potential to be useful in both clinical and epidemiological settings.

引用

页码：35 / 39

页数：5

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