Specific and sensitive diagnosis of schistosome infection: can it be done with antibodies?

被引:228
作者
Doenhoff, MJ [1 ]
Chiodini, PL
Hamilton, JV
机构
[1] Univ Wales, Sch Biol Sci, Bangor LL57 2UW, Gwynedd, Wales
[2] Hosp Trop Dis, London WC1E 6UA, England
[3] Univ London London Sch Hyg & Trop Med, London WC1E 7HT, England
[4] Univ Wales, Inst Biol Sci, Aberystwyth SY23 3DA, Ceredigion, Wales
基金
英国惠康基金;
关键词
D O I
10.1016/j.pt.2003.10.019
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
A simple, cheap, sensitive and specific assay for routine diagnosis of schistosome infection is not yet available. This review considers some of the advantages and disadvantages of parasitological microscopy, circulating-antigen detection and antibody-detection methods. Immunoassays for the detection of antibodies reactive against schistosome egg antigens have the potential to be useful in both clinical and epidemiological settings.
引用
收藏
页码:35 / 39
页数:5
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