Combined use of amino terminal-pro-brain natriuretic peptide levels and QRS duration to predict left ventricular systolic dysfunction in patients with dyspnea

被引：14

作者：

Sakhuja, R

Chen, AA

Anwaruddin, S

Baggish, AL

Januzzi, JL ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Massachusetts Gen Hosp, Div Cardiol, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Massachusetts Gen Hosp, Dept Med, Boston, MA 02115 USA

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2005年 / 96卷 / 02期

关键词：

D O I：

10.1016/j.amjcard.2005.03.056

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The combination of elevated amino-terminal pro-brain natriuretic peptide levels and wide QRS duration was highly sensitive and specific for the prediction of impaired left ventricular systolic function among a group of patients presenting with dyspnea to the emergency department. This strategy can be used to predict depressed function and target more formal evaluation with echocardiography in patients with dyspnea. (c) 2005 Elsevier Inc. All rights reserved.

引用

收藏

页码：263 / 266

页数：4

相关论文

共 13 条

[1] NT-proBNP: a new diagnostic screening tool to differentiate between patients with normal and reduced left ventricular systolic function [J].

Bay, M ;

Kirk, V ;

Parner, J ;

Hassager, C ;

Nielsen, H ;

Krogsgaard, K ;

Trawinski, J ;

Boesgaard, S ;

Aldershvile, J .

HEART, 2003, 89 (02) :150-154

[2] The N-terminal Pro-BNP investigation of dyspnea in the emergency department (PRIDE) study [J].

Januzzi, JL ;

Camargo, CA ;

Anwaruddin, S ;

Baggish, AL ;

Chen, AA ;

Krauser, DG ;

Tung, R ;

Cameron, R ;

Nagurney, JT ;

Chae, CU ;

Lloyd-Jones, DM ;

Brown, DF ;

Foran-Melanson, S ;

Sluss, PM ;

Lee-Lewandrowski, EL ;

Lewandrowski, KB .

AMERICAN JOURNAL OF CARDIOLOGY, 2005, 95 (08) :948-954

[3] QRS prolongation on surface ECG and brain natriuretic peptide as indicators of left ventricular systolic dysfunction [J].

Krüger, S ;

Filzmaier, K ;

Graf, J ;

Kunz, D ;

Stickel, T ;

Hoffmann, R ;

Hanrath, P ;

Janssens, U .

JOURNAL OF INTERNAL MEDICINE, 2004, 255 (02) :206-212

[4] Head-to-head comparison of the diagnostic utility of BNP and NT-proBNP in symptomatic and asymptomatic structural heart disease [J].

Mueller, T ;

Gegenhuber, A ;

Poelz, W ;

Haltmayer, M .

CLINICA CHIMICA ACTA, 2004, 341 (1-2) :41-48

[5] A prolonged QRS duration on surface electrocardiogram is a specific indicator of left ventricular dysfunction [J].

Murkofsky, RL ;

Dangas, G ;

Diamond, JA ;

Mehta, D ;

Schaffer, A ;

Ambrose, JA .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1998, 32 (02) :476-482

[6]

Otterstad JE, 1997, EUR HEART J, V18, P507

[7] THE UTILITY OF CLINICAL, ELECTROCARDIOGRAPHIC, AND ROENTGENOGRAPHIC VARIABLES IN THE PREDICTION OF LEFT-VENTRICULAR FUNCTION [J].

RIHAL, CS ;

DAVIS, KB ;

KENNEDY, JW ;

GERSH, BJ .

AMERICAN JOURNAL OF CARDIOLOGY, 1995, 75 (04) :220-223

[8] Application of NT-proBNP and BNP measurements in cardiac care: a more discerning marker for the detection and evaluation of heart failure [J].

Seino, Y ;

Ogawa, A ;

Yamashita, T ;

Fukushima, M ;

Ogata, K ;

Fukumoto, H ;

Takano, T .

EUROPEAN JOURNAL OF HEART FAILURE, 2004, 6 (03) :295-300

[9] Intraventricular conduction delay: a prognostic marker in chronic heart failure [J].

Shamim, W ;

Francis, DP ;

Yousufuddin, M ;

Varney, S ;

Pieopli, MF ;

Anker, SD ;

Coats, AJS .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 1999, 70 (02) :171-178

[10] Prognostic implications of increased QRS duration in patients with moderate and severe left ventricular systolic dysfunction [J].

Silvet, H ;

Amin, J ;

Padmanabhan, S ;

Pai, RG .

AMERICAN JOURNAL OF CARDIOLOGY, 2001, 88 (02) :182-+