The mucosal milieu creates tolerogenic dendritic cells and TRI and TH3 regulatory cells

被引：157

作者：

Weiner, HL ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Brigham & Womens Hosp, Ctr Neurol Dis, Boston, MA 02115 USA

来源：

NATURE IMMUNOLOGY | 2001年 / 2卷 / 08期

关键词：

D O I：

10.1038/90604

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Certain types of regulatory T cells are preferentially induced at mucosal surfaces to maintain tolerance. However, the mechanisms involved in their induction are unclear. New evidence suggests DCs orchestrate this mucosal tolerogenic immune response.

引用

页码：671 / 672

页数：2

共 14 条

[11] PREFERENTIAL INDUCTION OF POLYCLONAL IGA SECRETION BY MURINE PEYERS PATCH DENDRITIC CELL T-CELL MIXTURES
SPALDING, DM
WILLIAMSON, SI
KOOPMAN, WJ
MCGHEE, JR
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1984, 160 (03) : 941 - 946
[12] Resting respiratory tract dendritic cells preferentially stimulate T helper cell type 2 (Th2) responses and require obligatory cytokine signals for induction of Th1 immunity
Stumbles, PA
Thomas, JA
Pimm, CL
Lee, PT
Venaille, TJ
Proksch, S
Holt, PG
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1998, 188 (11) : 2019 - 2031
[13] Viney JL, 1998, J IMMUNOL, V160, P5815
[14] Zhang X, 2000, FASEB J, V14, pA1198

← 1 2 →