Multicellular dynamics during epithelial elongation

被引：64

作者：

Zallen, Jennifer A. ^{[1
]}

Blankenship, J. Todd ^{[1
]}

机构：

[1] Sloan Kettering Inst, Dev Biol Program, New York, NY 10065 USA

来源：

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY | 2008年 / 19卷 / 03期

关键词：

morphogenesis; axis elongation; Drosophila; polarity; adhesion;

D O I：

10.1016/j.semcdb.2008.01.005

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The reorganization of multicellular populations to produce an elongated tissue structure is a conserved mechanism for shaping the body axis and several organ systems. In the Drosophila germband epithelium, this process is accompanied by the formation of a planar polarized network of junctional and cytoskeletal proteins in response to striped patterns of gene expression. Actomyosin cables and adherens junctions are dynamically remodeled during intercalation, providing the basis for polarized cell behavior. Quantitative analysis of cell behavior in living embryos reveals unexpected cell population dynamics that include the formation of multicellular rosette structures as well as local neighbor exchange. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：263 / 270

页数：8

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