A possible mechanism determining the stability of spiculated red blood cells

被引：75

作者：

Iglic, A

机构：

[1] Faculty of Electrical Engineering, University of Ljubljana, 1000 Ljubljana

来源：

JOURNAL OF BIOMECHANICS | 1997年 / 30卷 / 01期

关键词：

cell shape; echinocyte; shear elasticity; bending energy; membrane skeleton;

D O I：

10.1016/S0021-9290(96)00100-5

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

In this work the stability of spiculated red blood cells, caned echinocytes, is studied. It is assumed that the stable echinocyte shape corresponds to the minimum of its membrane elastic energy. It is shown that if the membrane skeleton shear elasticity is not taken into account the calculated stable echinocyte shapes always have only one spicule. However, by considering the skeleton shear elastic energy also, the calculated stable echinocyte shapes have many spicula in agreement with experimental observations. Copyright (C) 1996 Elsevier Science Ltd.

引用

收藏

页码：35 / 40

页数：6

相关论文

共 37 条

[1] RELATIONS BETWEEN MEMBRANE MONOLAYERS IN SOME RED-CELL SHAPE TRANSFORMATIONS [J].

BECK, JS .

JOURNAL OF THEORETICAL BIOLOGY, 1978, 75 (04) :487-&

[2] SHAPE TRANSFORMATIONS OF GIANT VESICLES - EXTREME SENSITIVITY TO BILAYER ASYMMETRY [J].

BERNDL, K ;

KAS, J ;

LIPOWSKY, R ;

SACKMANN, E ;

SEIFERT, U .

EUROPHYSICS LETTERS, 1990, 13 (07) :659-664

[3] CRENATION AND CUPPING OF THE RED-CELL - A NEW THEORETICAL APPROACH .1. CRENATION [J].

BRAILSFORD, JD ;

KORPMAN, RA ;

BULL, BS .

JOURNAL OF THEORETICAL BIOLOGY, 1980, 86 (03) :513-529

[4] RED-CELL SHAPE FROM DISCOCYTE TO HYPOTONIC SPHEROCYTE - MATHEMATICAL DELINEATION BASED ON A UNIFORM SHELL HYPOTHESIS [J].

BRAILSFORD, JD ;

KORPMAN, RA ;

BULL, BS .

JOURNAL OF THEORETICAL BIOLOGY, 1976, 60 (01) :131-145

[5] PRESENT STATUS OF SPICULED RED-CELLS AND THEIR RELATIONSHIP TO DISCOCYTE-ECHINOCYTE TRANSFORMATION - CRITICAL REVIEW [J].

BRECHER, G ;

BESSIS, M .

BLOOD-THE JOURNAL OF HEMATOLOGY, 1972, 40 (03) :333-&

[6] MINIMUM ENERGY OF BENDING AS A POSSIBLE EXPLANATION OF BICONCAVE SHAPE OF HUMAN RED BLOOD CELL [J].

CANHAM, PB .

JOURNAL OF THEORETICAL BIOLOGY, 1970, 26 (01) :61-&

[7] CURVATURE ELASTICITY OF FLUID MEMBRANES - CATALOG OF VESICLE SHAPES [J].

DEULING, HJ ;

HELFRICH, W .

JOURNAL DE PHYSIQUE, 1976, 37 (11) :1335-1345

[8]

Evans E., 1978, Computer Times with Computacards

[9]

EVANS E, 1980, MECHANICS THERMODYNA, P160

[10] BENDING RESISTANCE AND CHEMICALLY-INDUCED MOMENTS IN MEMBRANE BILAYERS [J].

EVANS, EA .

BIOPHYSICAL JOURNAL, 1974, 14 (12) :923-931

← 1 2 3 4 →