A possible mechanism determining the stability of spiculated red blood cells

被引:75
作者
Iglic, A
机构
[1] Faculty of Electrical Engineering, University of Ljubljana, 1000 Ljubljana
关键词
cell shape; echinocyte; shear elasticity; bending energy; membrane skeleton;
D O I
10.1016/S0021-9290(96)00100-5
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
In this work the stability of spiculated red blood cells, caned echinocytes, is studied. It is assumed that the stable echinocyte shape corresponds to the minimum of its membrane elastic energy. It is shown that if the membrane skeleton shear elasticity is not taken into account the calculated stable echinocyte shapes always have only one spicule. However, by considering the skeleton shear elastic energy also, the calculated stable echinocyte shapes have many spicula in agreement with experimental observations. Copyright (C) 1996 Elsevier Science Ltd.
引用
收藏
页码:35 / 40
页数:6
相关论文
共 37 条
[31]   MEMBRANE BENDING ENERGY AND SHAPE DETERMINATION OF PHOSPHOLIPID-VESICLES AND RED BLOOD-CELLS [J].
SVETINA, S ;
ZEKS, B .
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 1989, 17 (02) :101-111
[32]   ON THE ROLE OF THE ELASTIC PROPERTIES OF CLOSED LAMELLAR MEMBRANES IN MEMBRANE-FUSION [J].
SVETINA, S ;
IGLIC, A ;
ZEKS, B .
TOXINS AND EXOCYTOSIS, 1994, 710 :179-191
[33]  
SVETINA S, 1996, CELL MOL BIOL LETT, V1, P67
[34]   THERMOELASTICITY OF RED BLOOD-CELL MEMBRANE [J].
WAUGH, R ;
EVANS, EA .
BIOPHYSICAL JOURNAL, 1979, 26 (01) :115-131
[35]   LOCAL AND NONLOCAL CURVATURE ELASTICITY IN BILAYER-MEMBRANES BY TETHER FORMATION FROM LECITHIN VESICLES [J].
WAUGH, RE ;
SONG, J ;
SVETINA, S ;
ZEKS, B .
BIOPHYSICAL JOURNAL, 1992, 61 (04) :974-982
[36]  
WAUGH RE, 1995, BIOMEDICAL ENG HDB, P474
[37]   ELASTIC DEFORMATIONS OF RED BLOOD-CELLS [J].
ZARDA, PR ;
CHIEN, S ;
SKALAK, R .
JOURNAL OF BIOMECHANICS, 1977, 10 (04) :211-221