11-isopropylcryptolepine:: A novel alkaloid isolated from Cryptolepis sanguinolenta characterized using submicro NMR techniques

被引：30

作者：

Hadden, CE

Sharaf, MHM

Guido, JE

Robins, RH

Tackie, AN

Phoebe, CH

Schiff, PL

Martin, GE

机构：

[1] Pharmacia & Upjohn Inc, Pharmaceut Dev, Rapid Struct Characterizat Grp, Kalamazoo, MI 49001 USA

[2] Al Azhar Univ, Fac Pharm, Dept Pharmacognosy & Nat Prod Ctr, Nasr City, Cairo, Egypt

[3] Ctr Sci Res Plant Med, Mampong Akwapim, Ghana

[4] Millipore Corp, Waters, Milford, MA 01757 USA

[5] Univ Pittsburgh, Sch Pharm, Dept Pharmaceut Sci, Pittsburgh, PA 15261 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 1999年 / 62卷 / 02期

关键词：

D O I：

10.1021/np980278t

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A new alkaloid has been isolated from extracts of the West African plant Cryptolepis sanguinolenta and identified by submicro NMR techniques as 11-isopropylcryptolepine (1). The unusual incorporation of the isopropyl group at the 11-position of the indolo[3,2-b]quinoline nucleus is suggestive of a mixed biosynthetic origin for the alkaloid.

引用

页码：238 / 240

页数：3

共 27 条

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