Endogenous type D retrovirus in a marsupial, the common brushtail possum (Trichosurus vulpecula)

被引：27

作者：

Baillie, GJ ^{[1
]}

Wilkins, RJ ^{[1
]}

机构：

[1] Univ Waikato, Dept Sci Biol, Hamilton, New Zealand

来源：

JOURNAL OF VIROLOGY | 2001年 / 75卷 / 05期

关键词：

D O I：

10.1128/JVI.75.5.2499-2507.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We have sequenced and characterized an endogenous type D retrovirus, which we have named TvERV(D), from the genome of an Australian marsupial, the common brushtail possum (Trichosurus vulpecula). Intact TvERV(D) gag, pro, pal, and ear open reading frames were detected in the possum genome. TvERV(D) was classified as a type D retrovirus, most closely related to those of Old World monkeys, New World monkeys, and mice, based on phylogenetic analyses and genetic organization. Approximately 30 TvERV(D) proviruses are present in the genomes of possums, as detected by Southern hybridization. However, variability in fragment patterns between possums was observed and suggests recent (or ongoing) retrotranspositional activity.

引用

页码：2499 / 2507

页数：9

共 35 条

[31] Complete nucleotide sequence of simian endogenous type D retrovirus with intact genome organization: Evidence for ancestry to simian retrovirus and baboon endogenous virus [J].