Unbreakable Codes in Electrospun Fibers: Digitally Encoded Polymers to Stop Medicine Counterfeiting

被引:63
作者
Huang, Chaobo [1 ]
Lucas, Bart [1 ]
Vervaet, Chris [2 ]
Braeckmans, Kevin [1 ]
Van Calenbergh, Serge [3 ]
Karalic, Izet [3 ]
Vandewoestyne, Mado [4 ]
Deforce, Dieter [4 ]
Demeester, Jo [1 ]
De Smedt, Stefaan C. [1 ]
机构
[1] Univ Ghent, Dept Pharmaceut, Lab Gen Biochem & Phys Pharm, Ghent Res Grp Nanomed, Ghent, Belgium
[2] Univ Ghent, Dept Pharmaceut, Pharmaceut Technol Lab, Ghent, Belgium
[3] Univ Ghent, Dept Pharmaceut, Med Chem Lab, Ghent, Belgium
[4] Univ Ghent, Dept Pharmaceut, Lab Pharmaceut Biotechnol, Ghent, Belgium
关键词
DIFFUSION MEASUREMENTS; MICROCARRIERS; TABLETS; DRUGS;
D O I
10.1002/adma.201000130
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Fluorescent polymer solutions can easily be electrospun into micrometer-sized fibers and subsequently encoded with long lasting digital codes by a photobleaching process. Such encoded fibers may find various applications; as illustrated in this report, placing encoded fibers in drug tablets may become a strategy to protect them from counterfeiting.
引用
收藏
页码:2657 / +
页数:7
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