Divergent and convergent evolution of NK-cell receptors

被引：141

作者：

Barten, R ^{[1
]}

Torkar, M ^{[1
]}

Haude, A ^{[1
]}

Trowsdale, J ^{[1
]}

Wilson, MJ ^{[1
]}

机构：

[1] Univ Cambridge, Dept Pathol, Div Immunol, Cambridge CB2 1QP, England

来源：

TRENDS IN IMMUNOLOGY | 2001年 / 22卷 / 01期

基金：

英国医学研究理事会; 英国惠康基金;

关键词：

D O I：

10.1016/S1471-4906(00)01802-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Natural killer (NK)-cell receptors specific for major histocompatibility complex (MHC) class I molecules have been identified in humans and mice. Some of the most important receptors are structurally unrelated in the two species: the murine Ly-49 receptors are C-type lectins. while human killer-cell inhibitory receptors (KIRs) belong to the immunoglobulin superfamily, Here, poland Barten and colleagues describe the divergent and convergent evolution of NK-cell receptors.

引用

页码：52 / 57

页数：6