Present and future of surface plasmon resonance biosensors

被引：1887

作者：

Homola, J ^{[1
]}

机构：

[1] Acad Sci Czech Republ, Inst Radio Engn & Elect, Prague, Czech Republic

来源：

ANALYTICAL AND BIOANALYTICAL CHEMISTRY | 2003年 / 377卷 / 03期

关键词：

optical sensor; biosensor; affinity biosensor; immunosensor; surface plasmon resonance;

D O I：

10.1007/s00216-003-2101-0

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Surface plasmon resonance (SPR) biosensors are optical sensors exploiting special electromagnetic waves-surface plasmon-polaritons-to probe interactions between an analyte in solution and a biomolecular recognition element immobilized on the SPR sensor surface. Major application areas include detection of biological analytes and analysis of biomolecular interactions where SPR biosensors provide benefits of label-free real-time analytical technology. This paper reviews fundamentals of SPR affinity biosensors and discusses recent advances in development and applications of SPR biosensors.

引用

页码：528 / 539

页数：12

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