Subfertility: causes, treatment and outcome

被引:67
作者
Adamson, GD
Baker, VL
机构
[1] Fertil Phys No Calif, Palo Alto, CA 94301 USA
[2] Stanford Univ, Sch Med, Stanford, CA 94305 USA
关键词
infertility; in vitro fertilization (IVF); ovulation; oligo-ovulation; gondadotrophins; endometriosis; adhesions; tubal surgery; congenital uterine abnormality; myoma; male factor infertility; intra-uterine insemination (IUI); oocyte donation; unexplained infertility;
D O I
10.1016/S1521-6934(02)00146-3
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Common causes of subfertility include ovulatory disorders, tubal disease, peritoneal adhesions, endometriosis, uterine abnormalities, abnormalities of sperm and advancing female age. Infertility is unexplained after thorough evaluation in about 5-10% of cases. Significant caveats must be attached to the interpretation of available data regarding infertility treatments. Successful ovulation induction in anovulatory women is possible for nearly all women except in cases of ovarian failure. Surgery is an option for some patients with tubal damage, adhesions, endometriosis and uterine abnormalities. Male factor infertility may be amenable to treatment of a specific cause, but is often empirical with the use of intra-uterine insemination (IUI) or in vitro fertilization (IVF). Egg donation is currently the most effective treatment available for age-related infertility when other treatments have not been successful. Couples with unexplained infertility may be effectively treated with ovulation induction plus IUI or IVF.
引用
收藏
页码:169 / 185
页数:17
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