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Towards a magnetic microarray for sensitive diagnostics

被引：75
作者：
Wang, SX
Bae, SY
Li, GX
Sun, SH
White, RL
Kemp, JT
Webb, CD
机构：
[1] Stanford Univ, Dept Mat Sci & Engn, Geballe Lab Adv Mat, Stanford, CA 94305 USA
[2] Stanford Univ, Dept Elect Engn, Stanford, CA 94305 USA
[3] IBM Corp, Thomas J Watson Res Ctr, Yorktown Hts, NY 10598 USA
[4] Stanford Univ, Genome Technol Ctr, Palo Alto, CA 94304 USA
来源：
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 2005年 / 293卷 / 01期
关键词：
magnetic microarray; MagArray; NanoTag; nanoparticles; spin valve; magnetic tunnel junction; biodetection; DNA detection;
D O I：
10.1016/j.jmmm.2005.02.054
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
We present proof-of-concept experiments and modeling towards a high-sensitivity magnetic microarray which "tags" a DNA fragment (or other biological samples) with a high-moment magnetic nanoparticle (NanoTag), which is in turn detected by a high-sensitivity spin valve (SV) or magnetic tunnel junction (MTJ) detector array. The detector can count the number of magnetic tags with a resolution of 1-20 magnetic NanoTags, potentially counting individual biomolecules. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码：731 / 736
页数：6
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