Total synthesis of apratoxin A

被引：97

作者：

Chen, JH ^{[1
]}

Forsyth, CJ ^{[1
]}

机构：

[1] Univ Minnesota, Dept Chem, Minneapolis, MN 55455 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 29期

关键词：

D O I：

10.1021/ja036050w

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Apratoxin A, a cyclodepsipeptide isolated from cyanobacterial Lyngbya spp, has been synthesized. The total synthesis features stereocontrolled access to the novel polyketide and the late-stage installation of the sensitive 2,4-disubstituted thiazoline moiety using an intramolecular Staudinger reduction/aza-Wittig process. Copyright © 2003 American Chemical Society.

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收藏

页码：8734 / 8735

页数：2

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