The isopropylsulfinyl group:: A useful chiral controller for the asymmetric aziridination of sulfinylimines and the organocatalytic allylation of hydrazones

被引：74

作者：

Fernández, I

Valdivia, V

Gori, B

Alcudia, F

Alvarez, E

Khiar, N

机构：

[1] Univ Seville, Fac Farm, Dept Quim Organ & Farmaceut, E-41012 Seville, Spain

[2] Univ Seville, CSIC, Inst Invest Quim, Seville 41092, Spain

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 07期

关键词：

D O I：

10.1021/ol050080h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A comparative study shows that the isopropylsulfinyl group for which an enantiodivergent and highly diastereoselective approach is reported behaves better than the tert-butylsulfinyl and p-tolylsulfinyl groups, both in terms of reactivity and stereoselectivity in the Corey-Chaykovsky reaction of chiral sulfinylimines and the organocatalytic allylation of acyl hydrazones.

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页码：1307 / 1310

页数：4

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